Tetrabutylammonium Fluoride → HCID 57911433, compound

HRID 1099177Notes

Reaction equation

HRID 1099177 reaction equation
CCCC[N+](CCCC)(CCCC)CCCC.[F-].[C:19]1([C:25]2=[CH:26][C:27]3[C:28]([CH:33]([O:36][Si](C(C)C)(C(C)C)C(C)C)[CH2:34][CH2:35]2)=[N:29][CH:30]=[CH:31][CH:32]=3)[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>C1COCC1>[C:19]1([C:25]2=[CH:26][C:27]3[C:28]([CH:33]([OH:36])[CH2:34][CH2:35]2)=[N:29][CH:30]=[CH:31][CH:32]=3)[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Participants

4

Reactant 2

HCID 2724141Tetrabutylammonium FluorideHCID 57911441HCID 57911441, compound

Product 1

HCID 57911433HCID 57911433, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

TBAF (1.041 mL, 1.041 mmol) was added to the THF (5 mL) solution of (E)-6-phenyl-9-(triisopropylsilyloxy)-8,9-dihydro-7H-cyclohepta[b]pyridine (0.2049 g, 0.521 mmol) at rt. The reaction was stirred at room temperature for 6 hours. The solvent was removed via vacuum to give the crude product. MS (ESI)[M+H+]=238.25.

Workup

  1. customThe solvent was removed via vacuum

Sources & evidence

ORD record
ord-24d656705f7f4fb1ab1ce762edf93259
Source dataset
uspto-grants-2012_03
Patent number
US08143403B2

Reaction notes

Loading…