Dimethylformamide → 2-(4-Chlorophenyl)-5-(1H-imidazol-1-yl)-4-[4-(4-pyridinyl)phenoxy]-3(2H)-pyridazinone

HRID 110241Notes

Reaction equation

HRID 110241 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([O:8][c:9]2[c:10](=[O:27])[n:11](-[c:20]3[cH:21][cH:22][c:23]([Cl:26])[cH:24][cH:25]3)[n:12][cH:13][c:14]2-[n:15]2[cH:16][n:17][cH:18][cH:19]2)[cH:6][cH:7]1.[CH2:38]([N:39]([CH:40]([CH3:41])[CH3:42])[CH:43]([CH3:44])[CH3:45])[CH3:46].[CH3:28][Sn:29]([c:30]1[cH:31][cH:32][n:33][cH:34][cH:35]1)([CH3:36])[CH3:37].[CH3:47][N:48]([CH3:49])[CH:50]=[O:51]>>[c:2]1(-[c:30]2[cH:31][cH:32][n:33][cH:34][cH:35]2)[cH:3][cH:4][c:5]([O:8][c:9]2[c:10](=[O:27])[n:11](-[c:20]3[cH:21][cH:22][c:23]([Cl:26])[cH:24][cH:25]3)[n:12][cH:13][c:14]2-[n:15]2[cH:16][n:17][cH:18][cH:19]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 81531DiisopropylethylamineHCID 11128458Pyridine, 4-(trimethylstannyl)-HCID 585853834-(4-bromophenyl)oxy-2-(4-chlorophenyl)-5-(1H-imidazol-1-yl)-3(2H)-pyridazinone

Product 1

HCID 585852262-(4-Chlorophenyl)-5-(1H-imidazol-1-yl)-4-[4-(4-pyridinyl)phenoxy]-3(2H)-pyridazinone

Sources & evidence

ORD record
ord-3daa5ca1e97b441aa5d2ae74f2b74772
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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