Ammonium → (3-(2-(tert-Butyldimethylsilyloxy)ethyl)thiophen-2-yl)(4-fluorophenyl)methanol
Reaction equation
[Br:6][c:7]1[s:8][cH:9][cH:10][c:11]1[CH2:12][CH2:13][O:14][Si:15]([CH3:16])([CH3:17])[C:18]([CH3:19])([CH3:20])[CH3:21].[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[Cl-:31].[F:22][c:23]1[cH:24][cH:25][c:26]([CH:27]=[O:28])[cH:29][cH:30]1.[NH4+:32]>>[c:7]1([CH:27]([c:26]2[cH:25][cH:24][c:23]([F:22])[cH:30][cH:29]2)[OH:28])[s:8][cH:9][cH:10][c:11]1[CH2:12][CH2:13][O:14][Si:15]([CH3:16])([CH3:17])[C:18]([CH3:19])([CH3:20])[CH3:21]Participants
7
Sources & evidence
- ORD record
- ord-bf8af1d2bb3246bda532562beb7c2983
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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