Tetrahydrofuran → Tert-butyl 4-[bromo(fluoro)methylidene]piperidine-1-carboxylate
Reaction equation
[Br:34][C:35]([F:36])([Br:37])[Br:38].[CH2:44]1[O:45][CH2:46][CH2:47][CH2:48]1.[CH3:39][CH2:40][Zn:41][CH2:42][CH3:43].[O:1]=[C:2]1[CH2:3][CH2:4][N:5]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:6][CH2:7]1.[c:15]1([P:16]([c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[cH:29][cH:30][cH:31][cH:32][cH:33]1>>[C:2]1(=[C:35]([Br:34])[F:36])[CH2:3][CH2:4][N:5]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:6][CH2:7]1Participants
6
Sources & evidence
- ORD record
- ord-b9550f732bca45319565f3558ddeb073
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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