HCID 63675640, compound → HCID 178422846, compound

HRID 1104750Notes

Reaction equation

HRID 1104750 reaction equation
Cc1ccc2c(cnn2C2CCCCO2)c1Br.F[B-](F)(F)c1ccc2ncccc2c1.[K+]>CC(=O)[O-].CC(=O)[O-].CCCCP([C@]12C[C@H]3C[C@H](C[C@H](C3)C1)C2)[C@]12C[C@H]3C[C@H](C[C@H](C3)C1)C2.CCc1cc(CC)cc(CC)c1.CCc1cccc(CC)c1.CO.Cc1ccccc1.O.[K+].[OH-].[Pd+2]>Cc1ccc2c(cnn2C2CCCCO2)c1-c1ccc2ncccc2c1

Participants

12

Reactant 2

HCID 63675640HCID 63675640, compoundHCID 71307646HCID 71307646, compound

Product 1

HCID 178422846HCID 178422846, compoundYield 55.51%

Reagents, catalysts & solvents 9

HCID 14797Potassium HydroxideReagentHCID 167845palladium(II) acetateCatalystHCID 178454859HCID 178454859, compoundCatalystHCID 887MethanolSolventHCID 962WaterSolvent3×HCID 1140TolueneSolventHCID 76021,3,5-TriethylbenzeneSolventHCID 88641,3-DiethylbenzeneSolventHCID 741954,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylInternal standard

Conditions

Temperature
100 °C

Sources & evidence

ORD record
ord-4435240ba27047498207f9880598e4fe
Source dataset
Rapid material-sparing screening of 5760 Suzuki-Miyaura coupling reactions
Original link
View source

Reaction notes

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