2,3-Dihydroxybutanedioic Acid → HCID 20553577, compound

HRID 1106202Notes

Reaction equation

HRID 1106202 reaction equation
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][N:2]=1.[CH2:11](I)[CH3:12].[OH-].[C:15]([OH:24])(=[O:23])[CH:16]([CH:18]([C:20]([OH:22])=[O:21])[OH:19])[OH:17]>C(#N)C>[C:20]([CH:18]([CH:16]([C:15]([O-:24])=[O:23])[OH:17])[OH:19])([O-:22])=[O:21].[CH2:11]([N+:2]1[CH:3]=[CH:4][C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[CH:1]=1)[CH3:12].[CH2:11]([N+:2]1[CH:3]=[CH:4][C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[CH:1]=1)[CH3:12]

Participants

6

Reactant 4

HCID 8752,3-Dihydroxybutanedioic AcidHCID 961HydroxideHCID 6340IodoethaneHCID 8405Isoquinoline

Product 1

HCID 20553577HCID 20553577, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Isoquinoline is reacted with ethyl iodide in acetonitrile; the halide intermediate is converted to the hydroxide with Rexyn 201, and then reacted with tartaric acid.

Sources & evidence

ORD record
ord-0970059489bb467e8278bc10b88e7bd0
Source dataset
uspto-grants-1982_01
Patent number
US04312367

Reaction notes

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