反应详情

25.2 g of lithium aluminium hydride were introduced into 100 ml of THF, and a solution of 54.2 g of methyl (4-propylidenecyclohexyl)acetate in 200 ml of THF was then added dropwise with stirring at such a rate that the reaction boiled gently. The mixture was then refluxed for a further 3 h, cooled to RT and hydrolysed dropwise with 50 ml of water. 18% hydrochloric acid was then added until the precipitate formed had dissolved. Conventional work-up gave 2-(4-propylidenecyclohexyl)ethanol (boiling point 110° C. at 10 mmHg).

1. temperatureThe mixture was then refluxed for a further 3 h
2. customformed
3. dissolutionhad dissolved