Hydrogen chloride-ethyl acetate → HCID 86755374, compound

HRID 1106664Notes

Reaction equation

HRID 1106664 reaction equation
[ClH:1].C(OCC)(=O)C.[CH3:8][N:9]([CH3:44])[CH2:10][CH2:11][CH2:12][N:13]([O:16][CH2:17][CH2:18][CH:19]1[CH2:24][CH2:23][CH2:22][CH2:21][N:20]1[C:25](=[O:43])[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42])[CH:14]=[O:15]>C(OCC)(=O)C>[ClH:1].[CH3:44][N:9]([CH3:8])[CH2:10][CH2:11][CH2:12][N:13]([O:16][CH2:17][CH2:18][CH:19]1[CH2:24][CH2:23][CH2:22][CH2:21][N:20]1[C:25](=[O:43])[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42])[CH:14]=[O:15]

Participants

4

Reactant 2

HCID 21866389Hydrogen chloride-ethyl acetateHCID 57217279HCID 57217279, compound

Product 1

HCID 86755374HCID 86755374, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

4N Hydrochloric acid/ethyl acetate solution (0.20 ml) was added to a solution of N-[3-(dimethylamino)propyl]-[2-(1-octadecanoyl-2-piperidyl)ethoxy]formamide (0.200 g) in ethyl acetate (2 ml). After being stirred for 15 minutes at room temperature, the reaction mixture was concentrated. The residue was recrystallized with ethyl acetate, thereby yielding the entitled compound (0.183 g) as white crystals.

Workup

  1. concentrationthe reaction mixture was concentrated
  2. customThe residue was recrystallized with ethyl acetate

Sources & evidence

ORD record
ord-2bca2175dbe64634a0bb93c3f4a84953
Source dataset
uspto-grants-2000_05
Patent number
US06057337

Reaction notes

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