HCID 9830126, compound → HCID 70103054, compound

HRID 1106674Notes

Reaction equation

HRID 1106674 reaction equation
[ClH:1].C(OCC)(=O)C.[CH2:8]([N:15]1[CH2:20][CH2:19][N:18]([C:21]([O:23][CH2:24][CH2:25][CH:26]2[CH2:31][CH2:30][CH2:29][CH2:28][N:27]2[C:32](=[O:50])[CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH3:49])=[O:22])[CH2:17][CH2:16]1)[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>C(OCC)(=O)C>[ClH:1].[CH2:8]([N:15]1[CH2:20][CH2:19][N:18]([C:21]([O:23][CH2:24][CH2:25][CH:26]2[CH2:31][CH2:30][CH2:29][CH2:28][N:27]2[C:32](=[O:50])[CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH3:49])=[O:22])[CH2:17][CH2:16]1)[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

Participants

4

Reactant 2

HCID 9830126HCID 9830126, compoundHCID 21866389Hydrogen chloride-ethyl acetate

Product 1

HCID 70103054HCID 70103054, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

4N Hydrochloric acid/ethyl acetate solution (1.24 ml) was added to a solution of 2-(1-octadecanoyl-2-piperidyl)ethyl 4-benzyltetrahydro- 1 (2H)-pyrazinecarboxylate (2.465 g) in ethyl acetate (25 ml). After being stirred for 30 minutes, the reaction mixture was concentrated. The residue was recrystallized with ethyl acetate, thereby yielding the entitled compound (2.041 g) as white solid.

Workup

  1. concentrationthe reaction mixture was concentrated
  2. customThe residue was recrystallized with ethyl acetate

Sources & evidence

ORD record
ord-9bc18a9073ae46f4a5d94ea02ec84c1b
Source dataset
uspto-grants-2000_05
Patent number
US06057337

Reaction notes

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