Oxalyl chloride → 4-[2-Benzyloxybenzylthio]benzoylchloride

HRID 1106821Notes

Reaction equation

HRID 1106821 reaction equation
[CH2:1]([O:8][C:9]1[CH:25]=[CH:24][CH:23]=[CH:22][C:10]=1[CH2:11][S:12][C:13]1[CH:21]=[CH:20][C:16]([C:17](O)=[O:18])=[CH:15][CH:14]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(Cl)(=O)C([Cl:29])=O>ClCCl>[CH2:1]([O:8][C:9]1[CH:25]=[CH:24][CH:23]=[CH:22][C:10]=1[CH2:11][S:12][C:13]1[CH:21]=[CH:20][C:16]([C:17]([Cl:29])=[O:18])=[CH:15][CH:14]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 65578Oxalyl chlorideHCID 226755514-[2-Benzyloxybenzylthio]benzoic acid

Product 1

HCID 226755374-[2-Benzyloxybenzylthio]benzoylchloride

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

4-[2-benzyloxybenzylthio]benzoic acid (6.3 g) and oxalyl chloride (2.26 g) were stirred in dichloromethane (100 ml) for 18 hours. The solvent was evaporated to give 4-[2-benzyloxybenzylthio]benzoylchloride which was dissolved in dichloromethane.

Workup

  1. customThe solvent was evaporated

Sources & evidence

ORD record
ord-5305b701737c40a39f385dff58cce21b
Source dataset
uspto-grants-2000_05
Patent number
US06057345

Reaction notes

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