2,2-Diphenylethylamine → HCID 22444194, compound

HRID 1107427Notes

Reaction equation

HRID 1107427 reaction equation
[C:1]1([CH:7]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH2:8][NH2:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[N:23]=[C:24]=[S:25]>CN(C=O)C>[Cl:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[NH:23][C:24]([NH:9][CH2:8][CH:7]([C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)[C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1)=[S:25]

Participants

4

Reactant 2

HCID 775752,2-DiphenylethylamineHCID 1231711-Chloro-2-isothiocyanatobenzene

Product 1

HCID 22444194HCID 22444194, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The compound was prepared substantially in accordance with the procedure detailed in Example 1, using 2,2-diphenylethylamine (1.61 g, 8.1 mmol) and 2-chlorophenyl isothiocyanate (1.1 ml, 8.2 mmol) in 30 ml of DMF. The crude material was purified by recrystallization (hexanes/EtOAc).

Workup

  1. customThe compound was prepared substantially in accordance with the procedure
  2. customThe crude material was purified by recrystallization (hexanes/EtOAc)

Sources & evidence

ORD record
ord-1b7391721ffb4afaa7278770dfd99280
Source dataset
uspto-grants-2000_05
Patent number
US06060484

Reaction notes

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