反应详情

Into a 1 l rounded-flask, were introduced 48.2 g of hexadecyl amine and 700 ml of ethanol. The mixture was heated to reflux, and then was gradually added 11 ml of 2-(2-chloroethoxy)ethanol. The mixture was refluxed for 3 hours and cooled to a room temperature. Thereto was added solution of KOH/ethanol to produce precipitates, which were removed by filtration. The filtrate was concentrated under reduced pressure, and then was recrystallized from ethanol, and dried to give 24.1 g of the title compound(Yield: 70%) as white powder, which was identified by IR and NMR. The results are shown in Table 1.

1. temperatureThe mixture was heated
2. temperatureto reflux
3. temperatureThe mixture was refluxed for 3 hours
4. customto produce
5. customprecipitates
6. customwhich were removed by filtration
7. concentrationThe filtrate was concentrated under reduced pressure
8. customwas recrystallized from ethanol
9. customdried