Sodium Bicarbonate → HCID 18432837, compound

HRID 1108233Notes

Reaction equation

HRID 1108233 reaction equation
[N:1]([O-:3])=O.[Na+].[NH2:5][C:6]1[N:11]([CH2:12][C:13]2[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=2)[C:10](=[O:19])[NH:9][C:8](=[O:20])[CH:7]=1.C(=O)(O)[O-].[Na+]>O.Cl>[NH2:5][C:6]1[N:11]([CH2:12][C:13]2[CH:14]=[CH:15][N:16]=[CH:17][CH:18]=2)[C:10](=[O:19])[NH:9][C:8](=[O:20])[C:7]=1[N:1]=[O:3]

Participants

6

Reactant 3

HCID 516892Sodium BicarbonateHCID 1526623HCID 1526623, compoundHCID 23668193Sodium Nitrite

Product 1

HCID 18432837HCID 18432837, compound

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 962WaterSolvent

Procedure

2.6 ml of 4N sodium nitrite was added to a solution of 2.35 g of 6-amino-1-(4-picolyl)-uracil in 25 ml of water and 4 ml of 5N HCl. After 15 minutes, 10 ml of 1N sodium bicarbonate was added. The solid was collected, washed and dried to give the title compound (2.15 g).

Workup

  1. customThe solid was collected
  2. washwashed
  3. customdried

Sources & evidence

ORD record
ord-455a5633c29241cdade799a5775b09b7
Source dataset
uspto-grants-2000_05
Patent number
US06066641

Reaction notes

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