Propargyl bromide → 3-(2-Fluoro-4-iodo-phenylamino)-1-prop-2-ynyl-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid ethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]([NH:15][c:16]2[c:17]([F:23])[cH:18][c:19]([I:22])[cH:20][cH:21]2)[c:8]2[cH:9][n:10][cH:11][cH:12][c:13]2[nH:14]1.[CH2:24]([C:25]#[CH:26])[Br:27].[CH2:28]1[CH2:29][CH2:30][C:31]2=[N:36][CH2:35][CH2:34][CH2:33][N:32]2[CH2:37][CH2:38]1.[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]([NH:15][c:16]2[c:17]([F:23])[cH:18][c:19]([I:22])[cH:20][cH:21]2)[c:8]2[cH:9][n:10][cH:11][cH:12][c:13]2[n:14]1[CH2:26][C:25]#[CH:24]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-d8588e36c44f426cbe46e2534fb1ad79
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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