Bis(2-chloroethyl) ether → HCID 60643053, compound

HRID 1109088Notes

Reaction equation

HRID 1109088 reaction equation
[OH-].[Na+].[I:3][C:4]1[CH:9]=[CH:8][C:7]([OH:10])=[CH:6][CH:5]=1.Cl[CH2:12][CH2:13][O:14][CH2:15][CH2:16]Cl>C(O)CCC>[I:3][C:4]1[CH:9]=[CH:8][C:7]([O:10][CH2:12][CH2:13][O:14][CH2:15][CH3:16])=[CH:6][CH:5]=1

Participants

5

Reactant 3

HCID 8115Bis(2-chloroethyl) etherHCID 108944-IodophenolHCID 14798Sodium Hydroxide

Product 1

HCID 60643053HCID 60643053, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent2×

Procedure

A mixture prepared by adding 3.08 g of sodium hydroxide and 40 ml of n-butanol to 15.4 g of 4-iodophenol was refluxed. 2 ml of n-butanol solution of 5.01 g of 1,5-dichloro-3-oxapentane was added dropwise to the above prepared mixture over a period of 5 minutes.

Workup

  1. customA mixture prepared
  2. temperaturewas refluxed

Sources & evidence

ORD record
ord-41efeb445c3945159d9585c07048a7c2
Source dataset
uspto-grants-1994_06
Patent number
US05319069

Reaction notes

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