Hexane → HCID 11831478, compound

HRID 1109774Notes

Reaction equation

HRID 1109774 reaction equation
[C:1](=[C:3]1[CH:12]=[CH:11][CH:10]=[C:5]([C:6]([O:8][CH3:9])=[O:7])[CH2:4]1)=O.[CH2:13]([Li])CCC.[CH3:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23]>[Cl-].C1([P+](C2C=CC=CC=2)(C2C=CC=CC=2)CC2C=CC=CC=2)C=CC=CC=1.O1CCCC1>[C:20]1(/[CH:13]=[CH:1]/[C:3]2[CH:4]=[C:5]([CH:10]=[CH:11][CH:12]=2)[C:6]([O:8][CH3:9])=[O:7])[CH:19]=[CH:18][CH:23]=[CH:22][CH:21]=1

Participants

6

Reactant 3

HCID 8058HexaneHCID 86747931HCID 86747931, compoundHCID 178418339Butyllithium

Product 1

HCID 11831478HCID 11831478, compound

Reagents, catalysts & solvents 2

HCID 70671Benzyltriphenylphosphonium chlorideCatalystHCID 8028TetrahydrofuranSolvent

Procedure

Using the procedure of Preparation H1, 2.37 g of triphenyl benzyl phosphonium chloride (Aldrich), 1.0 g of methyl 3-carbonylbenzoate and 2.44 ml of 2.5M solution of n-butyl lithium in hexane in 50 ml (total) of tetrahydrofuran gave 208 mg of the titled product, m.p. 108°-109° C.

Sources & evidence

ORD record
ord-a246fef99fae4428b3abccfdd87dece3
Source dataset
uspto-grants-1994_06
Patent number
US05322847

Reaction notes

Loading…