4-Nitrobenzaldehyde → 3-Aminobenzylamine

HRID 1111253Notes

Reaction equation

HRID 1111253 reaction equation
[N+:1](C1C=CC(C=O)=CC=1)([O-])=O.[N+:12]([C:15]1[CH:16]=[C:17]([CH:20]=[CH:21][CH:22]=1)[CH:18]=O)([O-])=O.[H][H]>>[NH2:12][C:15]1[CH:16]=[C:17]([CH:20]=[CH:21][CH:22]=1)[CH2:18][NH2:1]

Participants

4

Reactant 3

HCID 5414-NitrobenzaldehydeHCID 74493-NitrobenzaldehydeHCID 178418361HCID 178418361, compound

Product 1

HCID 46288313-AminobenzylamineYield 95.5%

Procedure

Reaction was carried out in the same manner as in Example 1 except that p-nitrobenzaldehyde was replaced by m-nitrobenzaldehyde Reaction was complete in 115 minutes, during which hydrogen (32 Nl) was absorbed. Post-treatment as in Example 1 was successively carried out to obtain M-aminobenzylamine having a purity of 99.91% (46.7 g, yield 95.5%, b.p. 131°-132° C./6 mm Hg).

Workup

  1. customReaction
  2. customwas absorbed

Sources & evidence

ORD record
ord-3c232afa18464a2895d50d0d24315332
Source dataset
uspto-grants-1990_12
Patent number
US04978792

Reaction notes

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