Triethylamine → 6-(2-Benzoyl-4-chlorobenzenesulphonamido)-capronitrile

HRID 1111352Notes

Reaction equation

HRID 1111352 reaction equation
C(N(CC)CC)C.[Cl:8][C:9]1[CH:14]=[CH:13][C:12]([S:15](Cl)(=[O:17])=[O:16])=[C:11]([C:19](=[O:26])[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH:10]=1.[NH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][C:33]#[N:34]>ClCCl>[C:19]([C:11]1[CH:10]=[C:9]([Cl:8])[CH:14]=[CH:13][C:12]=1[S:15]([NH:34][CH2:33][CH2:32][CH2:31][CH2:30][CH2:29][C:28]#[N:27])(=[O:17])=[O:16])(=[O:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 170796-AminohexanenitrileHCID 27566002-benzoyl-4-chloro-benzenesulfonyl Chloride

Product 1

HCID 542100966-(2-Benzoyl-4-chlorobenzenesulphonamido)-capronitrile

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

15 ml of redistilled triethylamine are added to 15.7 g of 4-chloro-2-benzoylbenzenesulphonyl chloride in 100 ml of anhydrous dichloromethane, and 5.6 g of 6-aminocapronitrile in 20 ml of dichloromethane are then added dropwise at 0° C.

Workup

  1. additionare then added dropwise at 0° C.

Sources & evidence

ORD record
ord-23516ffe816449acb98d3a0a33b39b85
Source dataset
uspto-grants-1990_12
Patent number
US04980349

Reaction notes

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