Triethylamine → HCID 22766277, compound

HRID 1111567Notes

Reaction equation

HRID 1111567 reaction equation
[CH2:1]([O:3][CH:4]([O:8][CH2:9][CH3:10])[CH2:5][CH2:6][NH2:7])[CH3:2].Br[CH2:12][CH:13]1[O:17][CH2:16][CH2:15][O:14]1.C(N(CC)CC)C>C1(C)C=CC=CC=1>[CH2:1]([O:3][CH:4]([O:8][CH2:9][CH3:10])[CH2:5][CH2:6][NH:7][CH2:12][CH:13]1[O:17][CH2:16][CH2:15][O:14]1)[CH3:2]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 780681,3-Dioxolane, 2-(bromomethyl)-HCID 5210291-Amino-3,3-diethoxypropane

Product 1

HCID 22766277HCID 22766277, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

3,3-Diethoxypropylamine (0.11 mole), 2-bromomethyl-1,3-dioxolane (0.1 mole), triethylamine (20 ml) and toluene (150 ml) are charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. The reaction is heated at reflux for a period of about 12 hours. After this time the reaction mixture is allowed to cool to room temperature and is filtered. The reaction mixture is then stripped of solvent and unreacted starting materials under reduced pressure to yield the desired product N-(3,3-diethoxypropyl)-N-(1,3-dioxolan-2-ylmethyl)amine.

Workup

  1. customequipped with a mechanical stirrer
  2. temperaturethermometer and reflux condenser
  3. temperatureThe reaction is heated
  4. temperatureat reflux for a period of about 12 hours
  5. filtrationis filtered

Sources & evidence

ORD record
ord-66cf28e0abef4df8a7a1c040c7081ffc
Source dataset
uspto-grants-1978_10
Patent number
US04118216

Reaction notes

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