Hydrochloric Acid → 2,2,2-Trifluoro-1-(4-pyridin-4-yl-phenyl)ethanol

HRID 111176Notes

Reaction equation

HRID 111176 reaction equation
[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[CH3:2][CH2:3][CH2:4][CH2:5][N+:6]([CH2:7][CH2:8][CH2:9][CH3:10])([CH2:11][CH2:12][CH2:13][CH3:14])[CH2:15][CH2:16][CH2:17][CH3:18].[ClH:41].[F-:1].[F:33][C:34]([F:35])([F:36])[Si:37]([CH3:38])([CH3:39])[CH3:40].[n:19]1[cH:20][cH:21][c:22](-[c:25]2[cH:26][cH:27][c:28]([CH:29]=[O:30])[cH:31][cH:32]2)[cH:23][cH:24]1>>[n:19]1[cH:20][cH:21][c:22](-[c:25]2[cH:26][cH:27][c:28]([CH:29]([OH:30])[C:34]([F:33])([F:35])[F:36])[cH:31][cH:32]2)[cH:23][cH:24]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 8028TetrahydrofuranHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 552549(Trifluoromethyl)trimethylsilaneHCID 6396734-(4-Pyridyl)benzaldehyde

Product 1

HCID 667424612,2,2-Trifluoro-1-(4-pyridin-4-yl-phenyl)ethanol

Sources & evidence

ORD record
ord-2994b756548b4eda904eba92512262d7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…