Hydrochloric Acid → [2-[4-[2-Fluoro-4-[5-(1,2-oxazol-3-yloxymethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperazin-1-yl]-2-oxoethyl] acetate

HRID 111194Notes

Reaction equation

HRID 111194 reaction equation
[C:36]([CH3:37])(=[O:38])[O:39][CH2:40][C:41](=[O:42])[Cl:43].[CH3:29][CH2:30][N:31]([CH2:32][CH3:33])[CH2:34][CH3:35].[Cl:44][CH2:45][Cl:46].[ClH:1].[ClH:2].[N:3]1([c:9]2[c:10]([F:28])[cH:11][c:12]([N:15]3[C:16](=[O:27])[O:17][CH:18]([CH2:20][O:21][c:22]4[n:23][o:24][cH:25][cH:26]4)[CH2:19]3)[cH:13][cH:14]2)[CH2:4][CH2:5][NH:6][CH2:7][CH2:8]1>>[N:3]1([c:9]2[c:10]([F:28])[cH:11][c:12]([N:15]3[C:16](=[O:27])[O:17][CH:18]([CH2:20][O:21][c:22]4[n:23][o:24][cH:25][cH:26]4)[CH2:19]3)[cH:13][cH:14]2)[CH2:4][CH2:5][N:6]([C:41]([CH2:40][O:39][C:36]([CH3:37])=[O:38])=[O:42])[CH2:7][CH2:8]1

Participants

6

Reactant 5

HCID 313Hydrochloric Acid2×HCID 6344DichloromethaneHCID 8471TriethylamineHCID 26297Acetoxyacetyl chlorideHCID 571103703-(3-Fluoro-4-piperazin-1-ylphenyl)-5-(1,2-oxazol-3-yloxymethyl)-1,3-oxazolidin-2-one

Product 1

HCID 57316774[2-[4-[2-Fluoro-4-[5-(1,2-oxazol-3-yloxymethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperazin-1-yl]-2-oxoethyl] acetate

Sources & evidence

ORD record
ord-d35e33531c3a41ebb18be90f1a59e142
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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