Isopropanol → 5-chloro-N-(4-chlorophenyl)-2-fluoro-6-morpholin-4-ylpyrimidin-4-amine
Reaction equation
[CH2:33]1[O:34][CH2:35][CH2:36][O:37][CH2:38]1.[CH:24]([N:25]([CH2:26][CH3:27])[CH:28]([CH3:29])[CH3:30])([CH3:31])[CH3:32].[CH:39]([OH:40])([CH3:41])[CH3:42].[Cl:9][c:10]1[c:11]([N:18]2[CH2:19][CH2:20][O:21][CH2:22][CH2:23]2)[n:12][c:13]([F:17])[n:14][c:15]1[F:16].[NH2:1][c:2]1[cH:3][cH:4][c:5]([Cl:6])[cH:7][cH:8]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([Cl:6])[cH:7][cH:8]1)[c:15]1[c:10]([Cl:9])[c:11]([N:18]2[CH2:19][CH2:20][O:21][CH2:22][CH2:23]2)[n:12][c:13]([F:17])[n:14]1Participants
6
Sources & evidence
- ORD record
- ord-d85ee01611124a95b11b50a60baef14c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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