Tetrahydrofuran → 3-[(2-Chloro-4-iodophenyl)amino]isonicotinic acid
Reaction equation
[CH3:11][Si:12]([N-:13][Si:14]([CH3:15])([CH3:16])[CH3:17])([CH3:18])[CH3:19].[Cl:21][c:22]1[c:23]([NH2:24])[cH:25][cH:26][c:27]([I:29])[cH:28]1.[F:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][cH:8][n:9][cH:10]1.[Li+:20].[O:30]1[CH2:31][CH2:32][CH2:33][CH2:34]1>>[c:2]1([NH:24][c:23]2[c:22]([Cl:21])[cH:28][c:27]([I:29])[cH:26][cH:25]2)[c:3]([C:4](=[O:5])[OH:6])[cH:7][cH:8][n:9][cH:10]1Participants
6
Sources & evidence
- ORD record
- ord-5532dcbbcd6747e5a44f0cccb4e6a4a4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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