Hydrochloric Acid → 7-(7-(benzyloxy)-6-methoxyquinolin-4-yloxy)-3,4-dihydro-2H-benzo[b][1,4]oxazine

HRID 1113159Notes

Reaction equation

HRID 1113159 reaction equation
[C:13](=[O:14])([O-:15])[O-:16].[CH2:19]([c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1)[O:26][c:27]1[c:28]([O:38][CH3:39])[cH:29][c:30]2[c:31]([Cl:37])[cH:32][cH:33][n:34][c:35]2[cH:36]1.[ClH:1].[Cs+:17].[Cs+:18].[O:2]1[c:3]2[c:4]([cH:8][cH:9][c:10]([OH:12])[cH:11]2)[NH:5][CH2:6][CH2:7]1.[O:40]=[CH:41][N:42]([CH3:43])[CH3:44]>>[O:2]1[c:3]2[c:4]([cH:8][cH:9][c:10]([O:12][c:31]3[c:30]4[cH:29][c:28]([O:38][CH3:39])[c:27]([O:26][CH2:19][c:20]5[cH:21][cH:22][cH:23][cH:24][cH:25]5)[cH:36][c:35]4[n:34][cH:33][cH:32]3)[cH:11]2)[NH:5][CH2:6][CH2:7]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 193865643,4-dihydro-2H-benzo[b][1,4]oxazin-7-olHCID 226465627-(Benzyloxy)-4-chloro-6-methoxyquinoline

Product 1

HCID 577371497-(7-(benzyloxy)-6-methoxyquinolin-4-yloxy)-3,4-dihydro-2H-benzo[b][1,4]oxazine

Sources & evidence

ORD record
ord-f2f21d767edf4248b0873235cda7e545
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…