Hydrochloric Acid → 1-(2,4-Difluorophenyl)-2,2,2-trifluoroethan-1-ol

HRID 111345Notes

Reaction equation

HRID 111345 reaction equation
[CH2:20]([N+:21]([CH2:22][CH2:23][CH2:24][CH3:25])([CH2:26][CH2:27][CH2:28][CH3:29])[CH2:30][CH2:31][CH2:32][CH3:33])[CH2:34][CH2:35][CH3:36].[CH2:38]1[O:39][CH2:40][CH2:41][CH2:42]1.[ClH:37].[F-:19].[F:11][C:12]([F:13])([F:14])[Si:15]([CH3:16])([CH3:17])[CH3:18].[F:1][c:2]1[c:3]([CH:4]=[O:5])[cH:6][cH:7][c:8]([F:10])[cH:9]1>>[F:1][c:2]1[c:3]([CH:4]([OH:5])[C:12]([F:11])([F:13])[F:14])[cH:6][cH:7][c:8]([F:10])[cH:9]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 8028TetrahydrofuranHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 737702,4-DifluorobenzaldehydeHCID 552549(Trifluoromethyl)trimethylsilane

Product 1

HCID 610868021-(2,4-Difluorophenyl)-2,2,2-trifluoroethan-1-ol

Sources & evidence

ORD record
ord-c719306d9cac4b5f85b76f5d7c5fa9dd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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