Tetrahydrofuran → 1-ethoxycarbonyl-4-(1-(5-hydroxymethylfur-2-ylmethyl)-1H-benzimidazol-2-yl)[1,4]diazepane
Reaction equation
[Al+3:34].[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[N:6]1[CH2:7][CH2:8][N:9]([c:13]2[n:14][c:15]3[c:16]([n:17]2[CH2:18][c:19]2[o:20][c:21]([C:24](=[O:25])[O:26][CH2:27][CH3:28])[cH:22][cH:23]2)[cH:29][cH:30][cH:31][cH:32]3)[CH2:10][CH2:11][CH2:12]1.[H-:33].[H-:36].[H-:37].[H-:38].[Li+:35].[O:39]1[CH2:40][CH2:41][CH2:42][CH2:43]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[N:6]1[CH2:7][CH2:8][N:9]([c:13]2[n:14][c:15]3[c:16]([n:17]2[CH2:18][c:19]2[o:20][c:21]([CH2:24][OH:25])[cH:22][cH:23]2)[cH:29][cH:30][cH:31][cH:32]3)[CH2:10][CH2:11][CH2:12]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-9092f9a14a554dff82a3697fe39ad116
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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