O-Xylene → N-(2-Benzothiazol-2-yl-5-methoxyphenyl)-3-fluoro-4-(2-piperidin-1-ylethoxy)benzamide
Reaction equation
[Br:1][c:2]1[c:3]([NH:10][C:11]([c:12]2[cH:13][c:14]([F:27])[c:15]([O:18][CH2:19][CH2:20][N:21]3[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26]3)[cH:16][cH:17]2)=[O:28])[cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1.[CH2:29]([Sn:30]([CH2:31][CH2:32][CH2:33][CH3:43])([c:34]1[s:35][c:36]2[c:37]([n:38]1)[cH:39][cH:40][cH:41][cH:42]2)[CH2:44][CH2:45][CH2:46][CH3:47])[CH2:48][CH2:49][CH3:50].[Pd:51]([Cl:52])[Cl:53].[c:54]1([P:55]([c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)[cH:68][cH:69][cH:70][cH:71][cH:72]1.[c:73]1([P:74]([c:75]2[cH:76][cH:77][cH:78][cH:79][cH:80]2)[c:81]2[cH:82][cH:83][cH:84][cH:85][cH:86]2)[cH:87][cH:88][cH:89][cH:90][cH:91]1.[c:92]1([CH3:93])[c:94]([CH3:95])[cH:96][cH:97][cH:98][cH:99]1>>[c:2]1(-[c:34]2[s:35][c:36]3[c:37]([n:38]2)[cH:39][cH:40][cH:41][cH:42]3)[c:3]([NH:10][C:11]([c:12]2[cH:13][c:14]([F:27])[c:15]([O:18][CH2:19][CH2:20][N:21]3[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26]3)[cH:16][cH:17]2)=[O:28])[cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-63b9243fa37d432ba3fc6cde2424b57e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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