Dimethylformamide → 1,1-Dimethylethyl 4-({4-chloro-5-[(1-methylethyl)oxy]-2-nitrophenyl}amino)-1-piperidinecarboxylate

HRID 1114843Notes

Reaction equation

HRID 1114843 reaction equation
[CH3:39][N:40]([CH3:41])[CH:42]=[O:43].[CH:30]([N:31]([CH:32]([CH3:33])[CH3:34])[CH2:35][CH3:36])([CH3:37])[CH3:38].[Cl:1][c:2]1[c:3]([O:12][CH:13]([CH3:14])[CH3:15])[cH:4][c:5]([F:11])[c:6]([N+:8](=[O:9])[O-:10])[cH:7]1.[NH2:16][CH:17]1[CH2:18][CH2:19][N:20]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:21][CH2:22]1>>[Cl:1][c:2]1[c:3]([O:12][CH:13]([CH3:14])[CH3:15])[cH:4][c:5]([NH:16][CH:17]2[CH2:18][CH2:19][N:20]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:21][CH2:22]2)[c:6]([N+:8](=[O:9])[O-:10])[cH:7]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 81531DiisopropylethylamineHCID 12682914-Amino-1-Boc-piperidineHCID 593939321-Chloro-4-fluoro-5-nitro-2-(propan-2-yloxy)benzene

Product 1

HCID 598501521,1-Dimethylethyl 4-({4-chloro-5-[(1-methylethyl)oxy]-2-nitrophenyl}amino)-1-piperidinecarboxylate

Sources & evidence

ORD record
ord-81608d3bb4db46cfb0e7158b90a19ff8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…