Potassium Cation → 7-Chloro-2-cyclopropylfuro[3,2-b]pyridine

HRID 1115322Notes

Reaction equation

HRID 1115322 reaction equation
[CH3:45][c:46]1[cH:47][cH:48][cH:49][cH:50][cH:51]1.[CH:12]1([B:15]([OH:16])[OH:17])[CH2:13][CH2:14]1.[CH:18]1([P:19]([CH:20]2[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25]2)[CH:26]2[CH2:27][CH2:28][CH2:29][CH2:30][CH2:31]2)[CH2:32][CH2:33][CH2:34][CH2:35][CH2:36]1.[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][cH:7]1)[cH:8][c:9]([I:11])[o:10]2.[K+:42].[K+:43].[K+:44].[OH2:52].[P:37]([O-:38])([O-:39])([O-:40])=[O:41]>>[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][cH:7]1)[cH:8][c:9]([CH:12]1[CH2:13][CH2:14]1)[o:10]2

Participants

8

Reactant 7

HCID 813Potassium Cation3×HCID 962WaterHCID 1061PhosphateHCID 1140TolueneHCID 75806TricyclohexylphosphineHCID 2760897Cyclopropylboronic acidHCID 66779473HCID 66779473, compound

Product 1

HCID 594273257-Chloro-2-cyclopropylfuro[3,2-b]pyridine

Sources & evidence

ORD record
ord-7a86e6103ff74188bf944c632b60b2ae
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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