Hydrochloric Acid → 2,6-Difluoro-N-{3-[3-(2-{[4-(methyloxy)-3-(4-methyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)pyrazolo[1,5-a]pyridin-2-yl]phenyl}benzamide
Reaction equation
[CH3:34][O:35][c:36]1[c:37]([N:43]2[CH2:44][CH2:45][N:46]([CH3:49])[CH2:47][CH2:48]2)[cH:38][c:39]([NH2:42])[cH:40][cH:41]1.[CH:51]([OH:52])([CH3:53])[CH3:54].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:17]3[cH:18][c:19]([NH:23][C:24]([c:25]4[c:26]([F:32])[cH:27][cH:28][cH:29][c:30]4[F:31])=[O:33])[cH:20][cH:21][cH:22]3)[n:10][n:11]3[c:12]2[cH:13][cH:14][cH:15][cH:16]3)[n:7]1.[ClH:50]>>[c:2]1([NH:42][c:39]2[cH:38][c:37]([N:43]3[CH2:44][CH2:45][N:46]([CH3:49])[CH2:47][CH2:48]3)[c:36]([O:35][CH3:34])[cH:41][cH:40]2)[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:17]3[cH:18][c:19]([NH:23][C:24]([c:25]4[c:26]([F:32])[cH:27][cH:28][cH:29][c:30]4[F:31])=[O:33])[cH:20][cH:21][cH:22]3)[n:10][n:11]3[c:12]2[cH:13][cH:14][cH:15][cH:16]3)[n:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-b32056dadcf346f9a766c0d61ddd2da8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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