Hydrochloric Acid → 1-Benzyloxycarbonyl-2-(1-aminoethyl)-4-tert-butyloxycarbonylpiperazine

HRID 1115975Notes

Reaction equation

HRID 1115975 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH:12]([CH:24]([CH3:25])[N:26]=[N+:27]=[N-:28])[CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]1.[Cl:49][CH2:50][Cl:51].[ClH:29].[c:30]1([P:31]([c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[c:38]2[cH:39][cH:40][cH:41][cH:42][cH:43]2)[cH:44][cH:45][cH:46][cH:47][cH:48]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH:12]([CH:24]([CH3:25])[NH2:26])[CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 11776TriphenylphosphineHCID 183428841-O-benzyl 4-O-tert-butyl 2-(1-azidoethyl)piperazine-1,4-dicarboxylate

Product 1

HCID 183428831-Benzyloxycarbonyl-2-(1-aminoethyl)-4-tert-butyloxycarbonylpiperazine

Sources & evidence

ORD record
ord-a2e2345a90c64609aa35b389d3db5e93
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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