Methanol → 2,6-difluoro-N-(5-(2-methyl-4,5,6,7-tetrahydrobenzo[b]thiophen-3-yl)pyridin-2-yl)benzamide
Reaction equation
[CH3:12][c:13]1[c:14](-[c:22]2[cH:23][cH:24][c:25]([NH2:28])[n:26][cH:27]2)[c:15]2[c:16]([s:17]1)[CH2:18][CH2:19][CH2:20][CH2:21]2.[CH3:46][OH:47].[CH:29]([N:30]([CH2:31][CH3:32])[CH:33]([CH3:34])[CH3:35])([CH3:36])[CH3:37].[Cl:38][CH2:39][Cl:40].[F:1][c:2]1[c:3]([C:4](=[O:5])[Cl:6])[c:7]([F:11])[cH:8][cH:9][cH:10]1.[Na+:49].[O:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1.[OH-:48]>>[F:1][c:2]1[c:3]([C:4](=[O:5])[NH:28][c:25]2[cH:24][cH:23][c:22](-[c:14]3[c:13]([CH3:12])[s:17][c:16]4[c:15]3[CH2:21][CH2:20][CH2:19][CH2:18]4)[cH:27][n:26]2)[c:7]([F:11])[cH:8][cH:9][cH:10]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-e38a25e6308745a3a90764c68986ff0e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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