Chloroform → 2-Chloro-6-(hydroxymethyl)-4-[2-(trimethylsilyl)ethynyl]pyridin-3-ol
Reaction equation
[CH2:19]1[O:20][CH2:21][CH2:22][CH2:23]1.[CH3:12][Si:13]([CH3:14])([CH3:15])[C:16]#[CH:17].[Cl:1][c:2]1[n:3][c:4]([CH2:10][OH:11])[cH:5][c:6]([I:9])[c:7]1[OH:8].[Cl:24][CH:25]([Cl:26])[Cl:27].[I-:18]>>[Cl:1][c:2]1[n:3][c:4]([CH2:10][OH:11])[cH:5][c:6]([C:17]#[C:16][Si:13]([CH3:12])([CH3:14])[CH3:15])[c:7]1[OH:8]Participants
6
Sources & evidence
- ORD record
- ord-40937d96fd6740449c42dc6279c25062
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
Loading…