Ammonia → 4-(1-t-Butoxycarbonylpiperidin-4-yloxy)-3-carbamoyl-5-methylnitrobenzene

HRID 1117425Notes

Reaction equation

HRID 1117425 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[c:16]([C:25](=[O:26])[OH:27])[cH:17][c:18]([N+:22](=[O:23])[O-:24])[cH:19][c:20]2[CH3:21])[CH2:12][CH2:13]1.[CH3:36][CH2:37][N:38]([CH2:39][CH3:40])[CH2:41][CH3:42].[Cl:28][C:29]([O:30][CH2:31][CH:32]([CH3:33])[CH3:34])=[O:35].[Cl:44][CH2:45][Cl:46].[NH3:43]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[c:16]([C:25](=[O:26])[NH2:38])[cH:17][c:18]([N+:22](=[O:23])[O-:24])[cH:19][c:20]2[CH3:21])[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 222AmmoniaHCID 6344DichloromethaneHCID 8471TriethylamineHCID 62365Isobutyl chloroformateHCID 18542573HCID 18542573, compound

Product 1

HCID 185427554-(1-t-Butoxycarbonylpiperidin-4-yloxy)-3-carbamoyl-5-methylnitrobenzene

Sources & evidence

ORD record
ord-0dcc1f7021054651854609a39cebbea7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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