Methyl iodide → 4-[(6-chloropyridin-3-yl)methyl]-7a-methyl-5,6,7,7a-tetrahydrofuro[3,2-b]pyridin-2(4H)-one
Reaction equation
[C:19]([Li:20])([CH3:21])([CH3:22])[CH3:23].[CH3:24][I:25].[CH3:31][CH2:32][CH2:33][CH2:34][CH3:35].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][N:9]2[C:10]3=[CH:17][C:16](=[O:18])[O:15][CH:11]3[CH2:12][CH2:13][CH2:14]2)[cH:6][n:7]1.[O:26]1[CH2:27][CH2:28][CH2:29][CH2:30]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][N:9]2[C:10]3=[CH:17][C:16](=[O:18])[O:15][C:11]3([CH3:19])[CH2:12][CH2:13][CH2:14]2)[cH:6][n:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-7eedb08b40d4460ea1c41c2b92ca9ff9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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