Tetrahydrofuran → 4'-(Trifluoromethyl)[1,1'-biphenyl]-3-methanol
Reaction equation
[Al+3:21].[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[F:1][C:2]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[cH:10][c:11]([C:12](=[O:13])[OH:14])[cH:15][cH:16][cH:17]2)[cH:7][cH:8]1)([F:18])[F:19].[H-:20].[H-:23].[H-:24].[H-:25].[Li+:22]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[cH:10][c:11]([CH2:12][OH:13])[cH:15][cH:16][cH:17]2)[cH:7][cH:8]1)([F:18])[F:19]Participants
6
Sources & evidence
- ORD record
- ord-ec49d7ab646247b18207fa05f5724800
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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