Bromide ion → 7-(4-Fluoro-benzyl)-6-hydroxy-5-methoxy-6-phenyl-9-triisopropylsilanyloxy-6,7-dihydro-pyrrolo[3,4-g]quinolin-8-one

HRID 1119408Notes

Reaction equation

HRID 1119408 reaction equation
[Br-:37].[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[CH3:50][CH2:51][O:52][C:53]([CH3:54])=[O:55].[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][N:7]2[C:8](=[O:34])[c:9]3[c:10]([O:32][CH3:33])[c:11]4[cH:12][cH:13][cH:14][n:15][c:16]4[c:17]([O:21][Si:22]([CH:23]([CH3:24])[CH3:25])([CH:26]([CH3:27])[CH3:28])[CH:29]([CH3:30])[CH3:31])[c:18]3[C:19]2=[O:20])[cH:35][cH:36]1.[c:38]1([Mg+:44])[cH:39][cH:40][cH:41][cH:42][cH:43]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][N:7]2[C:8]([OH:34])([c:38]3[cH:39][cH:40][cH:41][cH:42][cH:43]3)[c:9]3[c:10]([O:32][CH3:33])[c:11]4[cH:12][cH:13][cH:14][n:15][c:16]4[c:17]([O:21][Si:22]([CH:23]([CH3:24])[CH3:25])([CH:26]([CH3:27])[CH3:28])[CH:29]([CH3:30])[CH3:31])[c:18]3[C:19]2=[O:20])[cH:35][cH:36]1

Participants

6

Reactant 5

HCID 259Bromide ionHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 58928738HCID 58928738, compoundHCID 178507002HCID 178507002, compound

Product 1

HCID 589287567-(4-Fluoro-benzyl)-6-hydroxy-5-methoxy-6-phenyl-9-triisopropylsilanyloxy-6,7-dihydro-pyrrolo[3,4-g]quinolin-8-one

Sources & evidence

ORD record
ord-3e55c6af4a394b3f88c1405ba84eb2f9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…