Sodium ion → 11b-(2-Chlorophenyl)-7-(2-hydroxyethyl)-10-nitro-2,3,5,11b-tetrahydrooxazolo[3,2-d][1,4]benzodiazepin-6(7H)-one

HRID 1119605Notes

Reaction equation

HRID 1119605 reaction equation
[Br:28][CH2:29][CH2:30][OH:31].[CH3:32][N:33]([CH3:34])[CH:35]=[O:36].[Cl:1][c:2]1[c:3]([C:8]23[N:9]([CH2:10][C:11](=[O:22])[NH:12][c:13]4[c:14]2[cH:15][c:16]([N+:19](=[O:20])[O-:21])[cH:17][cH:18]4)[CH2:23][CH2:24][O:25]3)[cH:4][cH:5][cH:6][cH:7]1.[H-:26].[Na+:27]>>[Cl:1][c:2]1[c:3]([C:8]23[N:9]([CH2:10][C:11](=[O:22])[N:12]([CH2:29][CH2:30][OH:31])[c:13]4[c:14]2[cH:15][c:16]([N+:19](=[O:20])[O-:21])[cH:17][cH:18]4)[CH2:23][CH2:24][O:25]3)[cH:4][cH:5][cH:6][cH:7]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6228DimethylformamideHCID 108982-BromoethanolHCID 166653HydrideHCID 1231790211b-(2-chlorophenyl)-10-nitro-2,3,5,11b-tetrahydrooxazolo[3,2-d][1,4]benzodiazepin-6(7H)-one

Product 1

HCID 2140998311b-(2-Chlorophenyl)-7-(2-hydroxyethyl)-10-nitro-2,3,5,11b-tetrahydrooxazolo[3,2-d][1,4]benzodiazepin-6(7H)-one

Sources & evidence

ORD record
ord-c216f75ccb414343a1fb411856e1ea04
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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