Tetrahydrofuran → 5-cyclopropanesulfonyl-8-fluoro-7-(2-fluoro-4-iodophenyl)-2,3-dimethyl-2,7-dihydro-5H-imidazo[4,5-f]indazol-6-one
Reaction equation
[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[CH3:26][Si:27]([N-:28][Si:29]([CH3:30])([CH3:31])[CH3:32])([CH3:33])[CH3:34].[CH:35]1([S:38](=[O:39])(=[O:40])[Cl:41])[CH2:36][CH2:37]1.[F:1][c:2]1[c:3]2[c:4]([cH:5][c:6]3[c:7]([CH3:12])[n:8]([CH3:11])[n:9][c:10]13)[nH:13][c:14](=[O:24])[n:15]2-[c:16]1[c:17]([F:23])[cH:18][c:19]([I:22])[cH:20][cH:21]1.[Li+:25]>>[F:1][c:2]1[c:3]2[c:4]([cH:5][c:6]3[c:7]([CH3:12])[n:8]([CH3:11])[n:9][c:10]13)[n:13]([S:38]([CH:35]1[CH2:36][CH2:37]1)(=[O:39])=[O:40])[c:14](=[O:24])[n:15]2-[c:16]1[c:17]([F:23])[cH:18][c:19]([I:22])[cH:20][cH:21]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-850841254b7343ed9cd2c2ad50ceb34e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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