Dimethyl Sulfoxide → Tert-butyl 3-oxopyrrolidine-1-carboxylate

HRID 1119695Notes

Reaction equation

HRID 1119695 reaction equation
[CH3:7][S:8]([CH3:9])=[O:10].[CH:24]([N:25]([CH:26]([CH3:27])[CH3:28])[CH2:29][CH3:30])([CH3:31])[CH3:32].[Cl:1][C:2]([C:3]([Cl:4])=[O:5])=[O:6].[Cl:33][CH2:34][Cl:35].[OH:11][CH:12]1[CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]1>>[O:11]=[C:12]1[CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]1

Participants

6

Reactant 5

HCID 679Dimethyl SulfoxideHCID 6344DichloromethaneHCID 65578Oxalyl chlorideHCID 81531DiisopropylethylamineHCID 44169391-Boc-3-pyrrolidinol

Product 1

HCID 471360Tert-butyl 3-oxopyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-def69eb2bab4428a8a1de637685f9fb6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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