Triethylamine → Trimethylsilyl (4,4,7-trimethyl-thiochroman-6-yl) ethyne

HRID 1120442Notes

Reaction equation

HRID 1120442 reaction equation
[CH3:15][Si:16]([CH3:17])([CH3:18])[C:19]#[CH:20].[CH3:1][C:2]1([CH3:14])[CH2:3][CH2:4][S:5][c:6]2[cH:7][c:8]([CH3:13])[c:9]([Br:12])[cH:10][c:11]21.[CH3:26][CH2:27][N:28]([CH2:29][CH3:30])[CH2:31][CH3:32].[Cl:23][Pd:24][Cl:25].[I-:21].[Pd+2:22]>>[CH3:1][C:2]1([CH3:14])[CH2:3][CH2:4][S:5][c:6]2[cH:7][c:8]([CH3:13])[c:9]([C:20]#[C:19][Si:16]([CH3:15])([CH3:17])[CH3:18])[cH:10][c:11]21

Participants

7

Reactant 6

HCID 8471TriethylamineHCID 24290Palladium ChlorideHCID 30165Iodide IonHCID 66111TrimethylsilylacetyleneHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 156611176-Bromo-4,4,7-trimethylthiochroman

Product 1

HCID 15661126Trimethylsilyl (4,4,7-trimethyl-thiochroman-6-yl) ethyne

Sources & evidence

ORD record
ord-70a3fcc14a7547499133aeae693723a2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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