Dimethylformamide → tert-Butyl 4-((trimethylsilyl)oxy)-5,6-dihydropyridine-1(2H)-carboxylate

HRID 1120753Notes

Reaction equation

HRID 1120753 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11](=[O:14])[CH2:12][CH2:13]1.[CH3:15][Si:16]([CH3:17])([CH3:18])[Cl:19].[CH3:20][CH2:21][N:22]([CH2:23][CH3:24])[CH2:25][CH3:26].[O:27]=[CH:28][N:29]([CH3:30])[CH3:31]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]=[C:11]([O:14][Si:16]([CH3:15])([CH3:17])[CH3:18])[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 6397ChlorotrimethylsilaneHCID 8471TriethylamineHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

Product 1

HCID 10778540tert-Butyl 4-((trimethylsilyl)oxy)-5,6-dihydropyridine-1(2H)-carboxylate

Sources & evidence

ORD record
ord-e8ebfc5c27574bd682af75b0a615f897
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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