Hydrochloric Acid → 4-(2,4-Dichloro-5-methoxyanilino)-7-(5-formylthiophen-3-yl)quinoline-3-carbonitrile
Reaction equation
[C:34](=[O:35])([OH:36])[O-:37].[Cl:1][c:2]1[c:3]([NH:4][c:5]2[c:6]([C:25]#[N:26])[cH:7][n:8][c:9]3[cH:10][c:11](-[c:15]4[cH:16][s:17][c:18]([CH:20]5[O:21][CH2:24][CH2:23][O:22]5)[cH:19]4)[cH:12][cH:13][c:14]23)[cH:27][c:28]([O:32][CH3:33])[c:29]([Cl:31])[cH:30]1.[ClH:44].[Na+:38].[O:39]1[CH2:40][CH2:41][CH2:42][CH2:43]1>>[Cl:1][c:2]1[c:3]([NH:4][c:5]2[c:6]([C:25]#[N:26])[cH:7][n:8][c:9]3[cH:10][c:11](-[c:15]4[cH:16][s:17][c:18]([CH:20]=[O:21])[cH:19]4)[cH:12][cH:13][c:14]23)[cH:27][c:28]([O:32][CH3:33])[c:29]([Cl:31])[cH:30]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-837736c62b9e498e9364d7d71da89b2e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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