Hydrochloric Acid → (2-Amino-4,5-difluoro-phenyl)-pyridin-4-yl-methanone

HRID 1121384Notes

Reaction equation

HRID 1121384 reaction equation
[C:10](#[N:11])[c:12]1[cH:13][cH:14][n:15][cH:16][cH:17]1.[Cl:21][CH:22]=[C:23]([Cl:24])[Cl:25].[Cl:27][CH2:28][Cl:29].[ClH:18].[F:1][c:2]1[c:3]([F:9])[cH:4][c:5]([NH2:8])[cH:6][cH:7]1.[Na+:20].[OH-:19].[OH2:26]>>[F:1][c:2]1[c:3]([F:9])[cH:4][c:5]([NH2:8])[c:6]([C:10]([c:12]2[cH:13][cH:14][n:15][cH:16][cH:17]2)=[O:19])[cH:7]1

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 6344DichloromethaneHCID 6575TrichloroethyleneHCID 75064-CyanopyridineHCID 774693,4-Difluoroaniline

Product 1

HCID 22327317(2-Amino-4,5-difluoro-phenyl)-pyridin-4-yl-methanone

Sources & evidence

ORD record
ord-ae8698ce9a664858984369a2588bc809
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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