Methane → Tert-butyl 3,3-difluoro-1,6-diazaspiro[3.4]octane-6-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][C:10]2([C:11]([F:24])([F:25])[CH2:12][N:13]2[C:14]([O:15][CH2:16][c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)=[O:23])[CH2:26][CH2:27]1.[C:35].[CH3:33][OH:34].[O:28]1[CH2:29][CH2:30][CH2:31][CH2:32]1.[Pd:36]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][C:10]2([C:11]([F:24])([F:25])[CH2:12][NH:13]2)[CH2:26][CH2:27]1Participants
6
Sources & evidence
- ORD record
- ord-6772b8e2682d4ef4b588a5eee00e4b5f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…