Potassium Cation → 2-Chloro-6-(3-methoxyphenyl)pyridine

HRID 1121807Notes

Reaction equation

HRID 1121807 reaction equation
[C:20](=[O:21])([O-:22])[O-:23].[CH2:46]([CH2:47][O:48][CH3:49])[O:50][CH3:51].[CH3:1][O:2][c:3]1[cH:4][c:5]([B:9]([OH:10])[OH:11])[cH:6][cH:7][cH:8]1.[Cl:12][c:13]1[n:14][c:15]([Cl:19])[cH:16][cH:17][cH:18]1.[K+:24].[K+:25].[OH2:45].[c:26]1([P:27]([c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[cH:40][cH:41][cH:42][cH:43][cH:44]1>>[CH3:1][O:2][c:3]1[cH:4][c:5](-[c:15]2[n:14][c:13]([Cl:12])[cH:18][cH:17][cH:16]2)[cH:6][cH:7][cH:8]1

Participants

8

Reactant 7

HCID 813Potassium Cation2×HCID 962WaterHCID 80711,2-DimethoxyethaneHCID 11776TriphenylphosphineHCID 169892,6-DichloropyridineHCID 19660Carbonate IonHCID 2734370(3-Methoxyphenyl)boronic acid

Product 1

HCID 594893042-Chloro-6-(3-methoxyphenyl)pyridine

Sources & evidence

ORD record
ord-2f504d475f2847e4920e7fefc44d05e4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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