Water → 1-Tert-butyl 2-methyl 4-(methanesulfonyloxy)pyrrolidine-1,2-dicarboxylate

HRID 1122455Notes

Reaction equation

HRID 1122455 reaction equation
[C:13]([CH3:14])([CH3:15])([CH3:16])[O:17][C:18](=[O:19])[N:20]1[CH:21]([C:26](=[O:27])[O:28][CH3:29])[CH2:22][CH:23]([OH:25])[CH2:24]1.[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[CH3:8][S:9]([Cl:10])(=[O:11])=[O:12].[O:31]1[CH2:32][CH2:33][CH2:34][CH2:35]1.[OH2:30]>>[CH3:8][S:9](=[O:11])(=[O:12])[O:25][CH:23]1[CH2:22][CH:21]([C:26](=[O:27])[O:28][CH3:29])[N:20]([C:18]([O:17][C:13]([CH3:14])([CH3:15])[CH3:16])=[O:19])[CH2:24]1

Participants

6

Reactant 5

HCID 962WaterHCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 51482991-Tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate

Product 1

HCID 147726801-Tert-butyl 2-methyl 4-(methanesulfonyloxy)pyrrolidine-1,2-dicarboxylate

Sources & evidence

ORD record
ord-736f76ff1f7d47e987c8f1bbcbf1cb84
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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