Diethyl Ether → 2-Acetyl-6-bromopyridine

HRID 1122917Notes

Reaction equation

HRID 1122917 reaction equation
[Br:1][c:2]1[n:3][c:4]([Br:8])[cH:5][cH:6][cH:7]1.[CH2:9]([Li:10])[CH2:11][CH2:12][CH3:13].[CH3:14][N:15]([C:16]([CH3:17])=[O:18])[CH3:19].[CH3:20][CH2:21][O:22][CH2:23][CH3:24]>>[c:2]1([C:16]([CH3:17])=[O:18])[n:3][c:4]([Br:8])[cH:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 3283Diethyl EtherHCID 122742,6-DibromopyridineHCID 31374DimethylacetamideHCID 178418339Butyllithium

Product 1

HCID 112985782-Acetyl-6-bromopyridine

Sources & evidence

ORD record
ord-ed249b18b0554497b91be663543bb850
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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