Sodium ion → Tert-butyl 3-methoxypyrrolidine-1-carboxylate

HRID 1122986Notes

Reaction equation

HRID 1122986 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([OH:13])[CH2:11][CH2:12]1.[C:24]([O:25][CH2:26][CH3:27])(=[O:28])[CH3:29].[CH3:16][I:17].[CH3:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23].[H-:14].[Na+:15].[O:30]=[CH:31][N:32]([CH3:33])[CH3:34]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([O:13][CH3:18])[CH2:11][CH2:12]1

Participants

8

Reactant 7

HCID 923Sodium ionHCID 6228DimethylformamideHCID 6328Methyl iodideHCID 8058HexaneHCID 8857Ethyl AcetateHCID 166653HydrideHCID 44169391-Boc-3-pyrrolidinol

Product 1

HCID 20825945Tert-butyl 3-methoxypyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-28fa53646b2241f794f1e0641f018190
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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