Methyl iodide → 4-[[(6-chloropyridin-3-yl)methyl](2,2-difluoroethyl)amino]-5-methylfuran-2(5H)-one
Reaction equation
[C:20]([Li:21])([CH3:22])([CH3:23])[CH3:24].[CH3:25][I:26].[CH3:32][CH2:33][CH2:34][CH2:35][CH3:36].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][N:9]([C:10]2=[CH:11][C:12](=[O:15])[O:13][CH2:14]2)[CH2:16][CH:17]([F:18])[F:19])[cH:6][n:7]1.[O:27]1[CH2:28][CH2:29][CH2:30][CH2:31]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][N:9]([C:10]2=[CH:11][C:12](=[O:15])[O:13][CH:14]2[CH3:20])[CH2:16][CH:17]([F:18])[F:19])[cH:6][n:7]1Participants
6
Sources & evidence
- ORD record
- ord-e04ecb3b884148f6a61792384906d896
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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